South American Football Takes Center Stage on Wednesday: Sudamericana, Brasileirão, and MLS Action
Football fans can look forward to a packed schedule this Wednesday, July 22, featuring the Copa Sudamericana, Brasileirão, and MLS, including Inter Miami's match without star players.


Wednesday, July 22, brings a full slate of football action for fans across South America and beyond, with key matchups in the Copa Sudamericana, Brasileirão, and Major League Soccer (MLS). Following the recent World Cup, club competitions are now in full swing, offering a variety of games to follow throughout the day.
A significant highlight will be the return of Copa Sudamericana action, featuring the defending champions Lanús. The Argentine club, who entered the playoffs from the Copa Libertadores, will begin their title defense as they face Cienciano from Peru in the first leg of their playoff tie. This match marks a crucial point for Lanús as they aim to continue their continental success.
Key Fixtures This Wednesday
Beyond the Copa Sudamericana, several other leagues will see important games. The Brasileirão, Brazil’s top-flight league, continues its regular schedule with multiple fixtures that could impact the standings. Fans of South American football will also be following the Liga Pro in Ecuador, which has its own set of matches planned for the day.
MLS Action and Inter Miami
In North America, Major League Soccer (MLS) will also be in action. Notably, Inter Miami is scheduled to play against Chicago Fire. However, the Miami side will be without their star players Lionel Messi and Rodrigo de Paul, who have not yet rejoined the club following their participation in the 2026 World Cup. This absence could significantly influence the dynamic of the match.
European Qualifiers and Youth Football
The day’s schedule extends to Europe, with preliminary rounds for both the UEFA Champions League and the UEFA Europa Conference League. These early-stage matches are vital for clubs aiming to secure a spot in Europe’s most prestigious club competitions. Additionally, youth football will be featured, with matches including River Plate’s reserve team taking on Barracas Central. These games provide a platform for emerging talent and a glimpse into the future of club football.
What to Watch For
Fans interested in South American football will find a diverse selection of games. The Copa Sudamericana tie involving Lanús is particularly significant as it features a reigning champion embarking on their defense. The Brasileirão and Liga Pro matches offer regular-season drama, while the MLS game provides insight into how teams perform without their marquee players.
Key facts:
| Competition | Featured Match | Key Detail |
|---|---|---|
| Copa Sudamericana | Lanús vs. Cienciano | Lanús begins title defense |
| MLS | Inter Miami vs. Chicago Fire | Messi and De Paul absent |
| Brasileirão | Various Matches | Regular season continues |
| Champions League Qualifiers | Various Matches | Early European qualification |
Source: Ole – https://www.ole.com.ar/agenda-deportiva/partidos-hoy-miercoles-22-julio-horario-ver-futbol-vivo-tv-online-formaciones_0_mBJi5L1bnf.html
Source
Ole Original publication: 2026-07-22T09:00:20+00:00
FootballGames10 Desk
Editorial contributor.
